Efficacy of 200 IU versus 300 IU botulinum toxin intradetrusor injections in the treatment of neurogenic detrusor overactivity
نویسندگان
چکیده
منابع مشابه
300 IU vs. 200 IU of OnabotulinumtoxinA for detrusor overactivity
Botulinum toxin is probably the newest addition in the treatment armamentarium for overactive bladder , but, despite its late FDA approval, a significant experience exists in several centers around the world with this type of treatment. Because of its experimental status, the treatment with botulinum toxin is still lacking the much needed standardization, allowing for a great variety when it co...
متن کاملBotulinum toxin injections for treating neurogenic detrusor overactivity.
Neurogenic detrusor overactivity (NDO) is a disorder that can cause high intravesical pressure, decreased capacity, decreased bladder compliance, and upper urinary system damage. The current treatment options for NDO are established on the basis of agents that block parasympathetic innervation of the detrusor and inhibit involuntary bladder contractions. Several side effects, such as dryness of...
متن کاملBotulinum Toxin in Neurogenic Detrusor Overactivity
PURPOSE To evaluate the effects of botulinum toxin on urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity. METHODS Thirty four adult patients with spinal cord injury and detrusor overactivity were selected. The patients received 300 units of botulinum toxin type A. The endpoints evaluated with the episodes of urinary incontinence and measured the maximu...
متن کاملBotulinum toxin A (Botox) intradetrusor injections in adults with neurogenic detrusor overactivity/neurogenic overactive bladder: a systematic literature review.
OBJECTIVES This systematic literature review discusses the efficacy and safety of botulinum toxin type A (Botox) intradetrusor injections in adults with neurogenic detrusor overactivity (NDO) and urinary incontinence or overactive bladder symptoms of neurogenic origin (NOAB). METHODS A MEDLINE and EMBASE search for clinical studies with botulinum toxin A injected into the detrusor of adults w...
متن کاملIntravesical resiniferatoxin versus botulinum-A toxin injections for neurogenic detrusor overactivity: a prospective randomized study.
PURPOSE We investigated the effectiveness and safety of intravesical resiniferatoxin (Sigma Chemical Co., St. Louis, Missouri) and botulinum-A toxin injections into the detrusor muscle in a group of spinal cord injured patients with neurogenic detrusor overactivity unresponsive to conventional anticholinergic therapy. MATERIALS AND METHODS A total of 25 patients were randomly assigned to rece...
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ژورنال
عنوان ژورنال: Annals of Physical and Rehabilitation Medicine
سال: 2015
ISSN: 1877-0657
DOI: 10.1016/j.rehab.2015.07.295